RIBOMETRIX APPOINTS INDUSTRY VETERAN JOHN REARDON AS CHIEF SCIENTIFIC OFFICER AND EXPANDS MANAGEMENT TEAM

Dr. Reardon to lead strategic development of Ribometrix platform for novel RNA drug discovery
Appointment of two vice presidents to boost expanded research and discovery operations

#Ribometrix is excited to announce the addition of John Reardon, Ph.D., as our new Chief Scientific Officer. John has more than thirty years of experience in the biopharmaceutical industry, with the last twelve spent in operational roles within small, virtual or partially virtual therapeutic-focused companies.

#Ribometrix is excited to announce the addition of Don Hertzog, Ph.D. as our Vice President of Drug Discovery. Dr. Hertzog joins us from HemoShear Therapeutics where he was Head of Chemistry, leading all aspects of chemistry for HemoShear’s drug discovery programs in rare diseases.


#Ribometrix is excited to announce the addition of Bill Janzen as our new VP of Lead Discovery and Research Operations. Mr. Janzen has thirty years of experience in innovative drug discovery and has been a leader in the field of lead generation in academia, start-up ventures and large pharmaceutical companies.


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John Reardon
Don Hertzog
Bill Janzen

Ribometrix Announces $30 Million Series A Funding

Ribometrix, a biotechnology company developing small molecule therapeutics that directly target RNA to treat human diseases, announced today that it has completed a $30 million Series A financing to advance its discovery platform and internal pipeline of novel small molecule drugs that directly modulate RNA activity, as well as expand its team and business development activity...

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Ribometrix Team

Ribometrix Raises $7.5 Million

Ribometrix, Inc., a biotech company dedicated to discovering and developing small molecule modulators of RNA to treat disease, has raised $7.5 million in seed capital. The investment was led by SV Health Investors and Hatteras Venture Partners. Also participating were...

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Ribometrix Team

Small Molecules Against RNA

The start-up Ribometrix in North Carolina is scouring the three-dimensional, 3D, or tertiary, structures of RNA to find potential targets for small-molecule drugs. “If you’re going after tertiary structures, it looks like any other kind of drug discovery,” says Kevin Weeks, a biochemist at the University of North Carolina in Chapel Hill and founder of Ribometrix. “Just like with protein folding, you can find appropriate clefts and crevices withinRNA to target.” The company is searching for microRNAs and mRNAs associated with cancer, fibrosis, Huntington’s disease and multiple sclerosis. According to Weeks, the company has identified ten targets. “What gets me excited about these small molecules is if you draw structures, they look like normal drugs,” Weeks says. “They don’t look like anything special.” He adds that the company hopes to have multiple clinical leads by 2019....

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Ribometrix In C&EN

Ribometrix, and its technology are featured in a recent issue of Chemical & Engineering News, under the headline "The RNA Drug Hunters." The article mentions new probing technologies, such as SHAPE, invented in Professor Kevin Weeks' lab, which helps identify structured regions of RNA, potentionally amenable to drug targeting. The article goes on to quote Professor Weeks, who founded Ribometrix with his former graduate student Katie Warner, stating that this "field is about to explode."

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