19th Ave New York, NY 95822, USA

Careers

Careers at Ribometrix

Ribometrix is committed to delivering on the promise of addressing human disease through novel scientific insight into the structure of RNA. Unlike traditional drug discovery methodologies that target the product of RNA (proteins), we believe small molecule therapeutics can be designed to interact with RNA to deliver a meaningful therapeutic benefit to patients living with disease.

We are a team of individuals driven by the spirit of innovation, collaboration, empowerment, and integrity who are committed to the goal of helping patients with our novel therapeutic approach.

If you are looking for an opportunity to pioneer new science, collaborate with great people, and ultimately help those in need, then Ribometrix may be the place for you.

Scientist, RNA Biology

Durham


Position Summary

We are seeking a highly motivated Scientist to join our RNA Biology group and contribute to the development of the Ribometrix platform. This person will be part of a team that is responsible for expanding the Ribometrix platform with novel biochemical and cell-based assays and will have a key role in keeping Ribometrix at the cutting edge of the RNA-targeted small molecule space.

The position provides opportunities to explore the chemical biology of RNA while collaborating extensively with colleagues in the RNA Biology, Lead Discovery and Chemistry teams and to contribute to both the science and strategy of treating disease by targeting RNA. An ideal candidate will have demonstrated experience working with both in vitro transcribed and cell-derived RNA, cellular reporter assays, NGS libraries, and routine molecular biology work such as vector design and RT-qPCR.

Responsibilities include but are not limited to:

  • Design and execution of novel cellular and biochemical assays, including reporter assays
  • Execution and analysis of novel RNA-focused NGS experiments
  • Preparation and characterization of in vitro transcribed RNA, including custom labeling
  • Perform complex data analysis and interpretation to generate conclusions and next steps that drive the science forward
  • Support multiple tasks and maintain attention to detail in a fast-paced environment.
  • Stay up to date with the current scientific literature
  • Work collaboratively and lead by example to promote our Ribometrix Core Values: Integrity, Collaboration, Innovation, Empowerment, Resilience, and Fun.

Details

Project Manager

Durham


Position Summary

We are seeking a highly motivated Project Manager to help plan, track, coordinate, analyze and drive Ribometrix projects.

Essential Duties and Responsibilities include the following. Other duties may be assigned.

  • Assists with developing and executing sound, data-based project plans incorporating all activities required, including critical path analysis and resource loading where applicable.
  • Coordinates project teams from conception through IND.
  • Tracks projects to ensure completion on time and on budget.
  • Develops and maintains documentation and prepares agendas, minutes, decision/action logs.
  • Coordinates follow up on action logs to ensure timely execution.
  • Aids with identifying program risks and the development of risk mitigation strategies; works with others to resolve issues and remove barriers.
  • Supports teams in anticipating and resolving project issues/delays, understanding root causes of delays when they occur and implementing corrective actions to prevent repeat occurrences.
  • Applies best practices in the development, initiation, planning, execution, control and closing of projects.
  • Performs other duties as necessary.

Details

Sr. Scientist, Bioinformatics

Durham


Position Summary

We are seeking a highly motivated Senior Scientist to join our RNA Biology group and contribute to our bioinformatics capabilities. This person will be part of the bioinformatics team that is responsible for implementing and developing NGS software, developing and validating biological insights from complex datasets, and creating visualization methods and will have a key role in identifying and characterizing RNA targets for the Ribometrix platform.

The position provides opportunities to collaborate extensively with other members of the RNA Biology, Lead Discovery, and Chemistry teams and to contribute to both the science and strategy of treating disease by targeting RNA. An ideal candidate will have experience with algorithm design for NGS data, have the capability to integrate genomics data in novel analyses, and have excellent understanding of key bioinformatic resources, including ontologies.

Responsibilities include but are not limited to:

  • Design algorithms to answer biological questions and validate with statistical methods
  • Implement existing NGS software in workflows and develop software to meet unmet needs
  • Create unique visualization methods to communicate results to wet-lab biologists and leadership
  • Perform complex data analysis and interpretation to generate conclusions and next steps that drive the science forward
  • Support multiple tasks and maintain attention to detail in a fast-paced environmentWork collaboratively and lead by example to promote our Ribometrix Core Values: Integrity, Collaboration, Innovation, Empowerment, Resilience, and Fun
  • Details

Director or VP Human Resources

Durham, NC


Position Summary

Ribometrix is seeking to fill the role of Director/VP Human Resources with an experienced professional who has built young teams, managed company growth, and implemented policies, procedures and practices that support and facilitate the development of a biotech company’s most important resource, the individuals that bring the passion, innovation, character, and personality, Talent. These are the people that makes Ribometrix such a special place to work, and we are looking for a special individual to complement them and serve in this role.

Details

Sr. Scientist, Sample Management

Durham, NC


Position Summary

We are seeking a highly motivated, detail-oriented Senior Scientist to join our Lead Discovery group to lead the sample management team. This individual will be responsible for all aspects of sample management and will work with scientists, IT, and operations to manage and expand our sample management capabilities. This role is integral to helping us advance our RNA-small molecule drug discovery pipeline. Success in this position will require an individual who can perform and manage all aspects of sample management in a dynamic, fast-paced environment, with a drive to continually improve and execute within projected timelines, and who can collaborate effectively cross-functionally. Actual title will be commensurate with experience.

Responsibilities include but are not limited to:

  • Provide strategic leadership for sample management and guide growth of this functional area to support expanding inventory and research needs.
  • Manage personnel, resources, priorities, and external compound management CROs to effectively support and progress research efforts.
  • Oversee all logistical aspects of sample management including ordering, registration, receiving, request fulfillment, shipping, and physical inventory.
  • Assume accountability for our Laboratory Information Management System (LIMS) supporting sample management and small-scale automation used to fill requests.
  • Provide professional and technical support, directing work allocations, training and personnel development, to ensure the safe, reliable and timely completion of activities and tasks.
  • Work collaboratively and lead by example to promote our Ribometrix Core Values: Integrity, Collaboration, Innovation, Empowerment, Resilience, and Fun.

Details

Associate Director or Director, Lead Discovery

Durham, NC


Position Summary

We are seeking a highly motivated Associate Director or Director of Lead Discovery to join our team. The Associate Director or Director, Lead Discovery will report to the VP of Lead Discovery and will be accountable for leading programs and research activities to identify and progress RNA-targeted therapeutics. Success in this position will require an individual who has experience leading a group in a dynamic, fast-paced environment, with a drive to continually improve and execute within projected timelines, and who can collaborate effectively cross-functionally. Actual title will be commensurate with experience.

Responsibilities include but are not limited to:

  • Driving cutting edge science and leading drug discovery efforts.
  • Applying experience and innovation to all aspects of the drug discovery process.
  • Effectively managing personnel, internal and external resources, and timelines to progress programs.
  • Generating and communicating key insights that drive programs, and the science, forward.
  • Actively engaging in identifying targets and guiding biological strategy.
  • Working collaboratively at the interface of RNA biology and chemistry to add value to all research areas of the company.
  • Leading by example to promote our Ribometrix core values: Integrity, Collaboration, Innovation, Empowerment, Resilience, and Fun.

Details

Director or Associate Director, RNA Biology

Durham, NC


Position Summary

We are seeking a highly motivated Director or Associate Director of RNA Biology to join our team. The Director or Associate Director will report to the VP, RNA Biology and will be responsible for leading and/or managing multiple employees and research areas in the RNA Biology group. Success in this position will require an individual who has experience supervising a group in a dynamic, fast-paced environment, with a drive to continually improve and execute within projected timelines, and who can collaborate effectively cross-functionally. Actual title will be commensurate with experience.

Responsibilities include but are not limited to:

  • Managing one or more functional areas of the RNA Biology group, driving cutting edge science and effectively managing personnel, resources and timelines.
  • Leading programs as RNA Biology leader/program co-leader and communicating program status and challenges to the broader Ribometrix research organization.
  • Working collaboratively at the interface of RNA biology and drug discovery with Ribometrix scientists to add value to all research areas of the company.
  • Leading by example to promote our Ribometrix core values: Integrity, Collaboration, Innovation, Empowerment, Resilience, and Fun.

Details

Senior Scientist, Mass Spectrometry

Durham, NC


Position Summary

We are seeking a highly motivated Senior Scientist to join our Lead Discovery group and spearhead our mass spectrometry (MS)-based applications. This person will be part of a team that is responsible for discovering and characterizing RNA-small molecule interactors and will have a key role in identifying and progressing RNA-targeted therapeutics. The position provides opportunities to collaborate extensively with other members of the Lead Discovery, Chemistry, and RNA Biology teams and to contribute to both the science and strategy of treating disease by targeting RNA. An ideal candidate will have prior experience as a member of a team involved in drug discovery and working with validated processes and procedures.

Responsibilities include but are not limited to:

  • Establish, maintain, and troubleshoot MS-based platforms.
  • Develop and implement MS assays to support drug discovery screening and compound profiling activities.
  • Provide leadership to expand a MS-based strategy for identification and characterization of RNA/small molecule binders.
  • Perform complex data analysis and interpretation to generate conclusions and next steps that drive the science forward.
  • Implement high-throughput sample processing methods to facilitate timely data generation.
  • Support multiple tasks and maintain attention to detail in a fast-paced environment.
  • Train others on the theoretical and practical aspects of MS-based techniques and to perform MS assays.
  • Work collaboratively and lead by example to promote our Ribometrix Core Values: Integrity, Collaboration, Innovation, Empowerment, Resilience, and Fun.

Details

Research Associate II, RNA Biology

Durham, NC


Position Summary

We are seeking a Research Associate to join our RNA Biology team. This person will drive early RNA-small molecule discovery programs in our RNA Biology group. Identifying and characterizing the complex RNA structures targeted in our drug discovery pipeline. Success in this position will require an individual who is discovery-minded, with a drive to execute effectively and who can collaborate effectively with other members of the RNA Biology team and the wider organization. The Research Associate will have a pivotal role in providing support to the RNA biology group to elucidate novel RNA structures for drug discovery.

Responsibilities include but are not limited to:

  • Apply cutting-edge RNA technologies to identify complex RNA structures for small molecule targeting
  • Implement, optimize and troubleshoot experiments to analyze and characterize new drug targets
  • Maintain a high-quality lab notebook and maintain SOPs

Details

Research Associate, RNA Biology

Durham, NC


Position Summary

We are seeking a Research Associate to join our RNA Biology team. This person will drive early RNA-small molecule discovery programs in our RNA Biology group. Identifying and characterizing the complex RNA structures targeted in our drug discovery pipeline. Success in this position will require an individual who is discovery-minded, with a drive to execute effectively and who can collaborate effectively with other members of the RNA Biology team and the wider organization. The Research Associate will have a pivotal role in providing support to the RNA biology group to elucidate novel RNA structures for drug discovery.

Details

Our Founders
Dr. Kevin Weeks
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